Agricultural University of Athens  |   X-ray Diffraction
 
DESCRIPTION

The 3D structure determination of proteins using X-ray Diffraction is one of the core services of our Infrastructure. Knowledge of the 3D structure of macromolecular targets of pharmaceutical and biotechnological interest and their complexes with small molecules or other proteins may reveal the structure-function relationships that dictate their mechanism of action. Proteins participate in a plethora of metabolic pathways and controlling their interactions with their counterparts or bioactive compounds may allow the development of therapeutic interventions with significant socioeconomic impact.

Potential users: Scientists working in academic/research organizations, health sciences, hospitals, industries (pharmaceutical, food, agricultural, biofuel, paper, chemical) and SMEs.

Agricultural University of Athens
LOCATION:   Athens | https://www2.aua.gr/en
RELEVANT STAFF:   Elias Eliopoulos , Kostas Bethanis
SERVICE DETAILS:  

Visit the provider's website: http://inspired.aua.gr/instruct/

RELEVANT EQUIPMENT:  
EQUIPMENT UNIT:  
HP Intel Xeon by HP
TYPE:   Bioinformatics Server
ADDITIONAL INFO:  
 
LOCATION:   75 Iera Odos, Athens 118 55, Greece, Agricultural University of Athens, Hassiotes Build., 1st Floor, Biotechnology Dept., Genetics Lab
DESCRIPTION:  

Server consists of 24 units of 8-core Intel Xeon 2.8GHz workstations with 32GB internal memory each.


FUNDER:   INSPIRED-AUA GSRT
 
 
 
EQUIPMENT UNIT:  
D8 Venture by Bruker
TYPE:   X-ray Crystallography system
ADDITIONAL INFO:  
 
LOCATION:   75 Iera Odos, Athens 118 55, Greece, Agricultural University of Athens, Hassiotes Build., 1st Floor, Biotechnology Dept., Physics Lab
DESCRIPTION:  

The D8 Venture system includes:

IμS microfocus X-ray source, Cu radiation, air cooled

Four-circle goniometer, computer-controlled, crystal-detector distance = 35-240mm, sphere of confusion of less than 7 micrometer

Detector PHOTON 100, CMOS technology, air-cooled, 100 x 100mm active area, 240e/Cu sensitivity, shutterless data collection

800 Series Cryostream cooler, Oxford Cryosystems, AD51 Dry Air Unit, Integrated Autofill system, 60 lt and 150 lt dewar vessels.

APEX3 and PROTEUM software


FUNDER:   NSRF 2007-2013, Regional Operational Programme Attica
 
 
 
RELEVANT EXPERTISE: